PROSIT Nephropathy Diabetes Models

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ShannonB Model

Structure of the PROSIT Nephropathy Diabetes Disease Model nick named "Shannon B".

Latest Release: 15. October 2018

Latest Version: PROSIT Nephropathy Type 2 Diabetes Disease Model 2018B Germany

Summary: Shannon B: first release of the Danube B structure based on the Shannon A methodology with updated inputs. The model is open for discussion: use the discussion link at the top of this page.

Methodology: Markov model (Markov process)

Health Economic Perspective: flexible, dependent on user specification

Time Horizon: 80 cycles; currently defined as annual time steps

Patient Cohort: realistic diabetes cohort for Germany and type 2 diabetes mellitus based on the ProValue study. Divided into up to 16 sub-cohorts. Cohort specifications can be edited freely.

Costs: summary costs for Germany are included based on the KODIM Cost study and results being inflationed to the year 2015. Costs can be edited freely.

Other specifications: the model supports QALYS, and discounting of both costs and effects. The half-cycle correction is implemented as within-cycle correction.

Team Members: Fabian Sailer, Monika Pobiruchin, Jonathan Schwarz, Wendelin Schramm

Previous Versions: PROSIT Nephropathy Type 2 Diabetes Disease Model 2016B Germany (from 11. July 2017)

ShannonA Model

This model version has been replaced by the Shannon B model and is not supported any more since 2017.

Latest Release: October 2012

Latest Version: PROSIT Nephropathy Type 2 Diabetes Disease Model 2012A Germany RC1

Summary: Shannon A: New release of the Danube A structure based on a new methodology that allows to include patient sub-groups. The Release Candidates are open for discussion: use the discussion link at the top of this page.

Team Members: Christian Weiß, Jens Attumalil, Selcan Ipek, Keno März, Monika Pobiruchin, Wendelin Schramm

DanubeB Model

This model version has been replaced by the Shannon A model and is not supported any more since 2012.

Discontinued Danube B Version: The version below is based on the pre 2012 modelling procedures and has been abandoned.

Summary: Introduction of an additional transition from macroalbuminuria to microalbuminuria to the Danube A structure.

Team Members: SL, Wendelin Schramm

DanubeA Model

This model version has been replaced by the Danube B model and is not supported any more since 2010.

Structure of the PROSIT Nephropathy Diabetes Disease Model 2008A, nick named as Danube A. The Shannon A model and the Danube A model have the same structure but different approaches of implemenation.

Last Release: 08.01.2008

Last Version: PROSIT NEPHROPATHY TYPE 2 DIABETES DISEASE MODEL 2008A Germany RC1

Summary: n.a.

Team Members: Natalie Krämer, Sabrina Lang, Monika Pobiruchin, Michael Schöll, Wendelin Schramm, Björn Schreiweis, Benjamin Trinczek, Christian Weber