PROSIT Coronary Heart Disease Models

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Previously published as PROSIT Myocardial Infarction Models


MissouriB Model

Structure of the PROSIT Myocardial Infarction Diabetes Disease Model Missouri A/B

Latest Release: 14. October 2018

Latest Version: PROSIT CHD Type 2 Diabetes Disease Model 2018B Germany

Summary: New release of the cardiovascular disease model based on a similar methodology as Missouri A that allows to include patient sub-groups. The model is open for discussion: use the discussion link at the top of this page.

Methodology: Markov model (Markov process)

Health Economic Perspective: flexible, dependent on user specification

Time Horizon: 80 cycles; currently defined as annual time steps

Patient Cohort: realistic diabetes cohort for Germany and type 2 diabetes mellitus based on the ProValue study. Divided into up to 16 sub-cohorts. Cohort specifications can be edited freely.

Costs: summary costs for Germany are included based on the KODIM Cost study and results being inflationed to the year 2015. Costs can be edited freely.

Other specifications: the model supports QALYS, and discounting of both costs and effects. The half-cycle correction is implemented as within-cycle correction.

Team Members: Fabian Sailer, Monika Pobiruchin, Wendelin Schramm

Previous Versions: PROSIT CHD Type 2 Diabetes Disease Model 2016B Germany (from 28. September 2017)

MissouriA Model

Discontinued version Missouri A: Missouri A has been abandoned with the release of the Missouri B model.

Latest Version: PROSIT CHD Type 2 Diabetes Disease Model 2013A Germany RC1

Summary: First release of the Missouri A structure based on a new methodology that allows to include patient sub-groups.

Team Members: Christian Weiß, Kurt Neeser, Jens Attumalil, Wendelin Schramm

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